Avandaryl (Rosiglitazone/Glimepiride) for Diabetes

Overview
Avandaryl is a prescription drug approved by the Food and Drug Administration (FDA) to help improve blood glucose control in adults with type 2 diabetes. Avandaryl is considered an adjunct treatment to diet and exercise.

Avandaryl is a combination drug composed of the drugs Rosiglitazone, the active ingredient in Avandia, and Glimepiride, the active ingredient in Amaryl. Rosiglitazone is a thiazolidinedione, also known as a glitazone. Rosiglitazone is believed to work by decreasing the amount of glucose released by the liver and making insulin more effective in muscle and fat tissues. Glimepiride is a sulfonylurea. Glimepiride is believed to work by increasing the amount of insulin released by the pancreas.

How do I take it?
Prescribing information states that Avandaryl is generally taken once daily with the morning meal.

Avandaryl comes in tablet form.

Side effects
The FDA-approved label for Avandaryl lists common side effects including sore throat and headache.

Rare but serious side effects listed for Avandaryl include systemic allergic reaction.