There was/is two formulations of NPH (which is just the initials of some dude that created the stuff).

The original was long acting (animal sourced - cows) and still available in Canada (but have to ask specifically) then they changed to an intermediate, still NPH but sold as Humulin N - lab grown human insulin - 12-18 hour total life.

So for the long acting version the Doc has to specify NPH and not Humulin

My Dad used the original NPH for a few years before switching over to the 70/30 Humulin

I use Toujeo its almost like Tresiba this one u inject every 24 hours. I have severe low sugar readings like 1.2 daily and with the Toujeo and Apidra on a Sliding Scale it helps me a lot. Was on Tresiba but it didnt help me much. But speak to your doctor and find out if this would work for you. Have heard about Insulin you only use once a few days but cant remember the name at this stage

@A DiabetesTeam Member you may want to take a look at a very "old" insulin called NPH which used to be the only Basal until a couple decades back.

Onset is 1 to 3 hours, lasts a total of 24, peaks at 6 to 8 hours.

But, it is also the long acting "most likely" to induce a low. Lantus et al were (engineered) to make them safer.

Mentioned Users

A Diabete...

I have been on Humalog 25/75 mix now for 13 years works well

As far as i know,no long term insulin has a peak,but will do some investigation.