GLP-1 RECEPTOR AGONIST
Overview
Liraglutide is approved by the U.S. Food and Drug Administration (FDA) for improving blood sugar control in adults and children aged 10 years and older with type 2 diabetes. This treatment is used alongside diet and exercise to achieve better glycemic control. Liraglutide is a drug referencing Victoza, a formulation of liraglutide, meaning it has been evaluated and approved based on its equivalence in safety, quality, and effectiveness to the brand-name product.
As a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide mimics a hormone that helps regulate blood sugar by increasing insulin secretion in response to elevated glucose levels. It also slows digestion, which aids in better blood sugar management.
How do I take it?
Prescribing information states that liraglutide is administered as a once-daily subcutaneous (under the skin) injection, usually in the abdomen, thigh, or upper arm. The dosage schedule typically begins with a lower dose, gradually increasing to a maintenance dose to minimize side effects. Liraglutide should be administered exactly as prescribed by a health care provider.
Side effects
Common side effects of liraglutide include nausea, diarrhea, vomiting, decreased appetite, indigestion (dyspepsia), and constipation.
Rare but serious side effects may include thyroid C-cell tumors, pancreatitis (inflammation of the pancreas), hypoglycemia (low blood sugar) when used with other medications like insulin, gallbladder disease, hypersensitivity reactions, and kidney impairment. People with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should not use liraglutide.
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