Glucotrol (Glipizide)
- Type: Sulfonylurea
- Mechanism: Increases the amount of insulin released by the pancreas
- Usage: Generally taken 30 minutes before meals, once daily or more frequently.
- Common Side Effects: Hypoglycemia (low blood sugar), nausea, vomiting, stomach pain, gas, dizziness, drowsiness, headache, loss Show Full Answer

Glucotrol (Glipizide):
- Type: Sulfonylurea
- Mechanism: Increases the amount of insulin released by the pancreas.
- Usage: Generally taken 30 minutes before meals, once daily or more frequently.
- Common Side Effects: Hypoglycemia (low blood sugar), nausea, vomiting, stomach pain, gas, dizziness, drowsiness, headache, loss of appetite, itching, and rash.
- Serious Side Effects: Jaundice and systemic allergic reactions.

Metformin:
- Type: Biguanide
- Mechanism: Decreases the amount of glucose produced by the liver and makes muscle tissue more sensitive to insulin.
- Usage: Generally taken once daily with the last meal of the day.
- Common Side Effects: Diarrhea, nausea, gas, stomach pain, and upset stomach.
- Serious Side Effects: Lactic acidosis (when the tissues and blood become too acidic) and systemic allergic reaction.

Both medications are adjunct treatments to diet and exercise for managing type 2 diabetes.

 This AI-generated response comes from DiabetesTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

Metformin for Diabetes | DiabetesTeam

Glucovance (Glyburide/Metformin) for Diabetes | DiabetesTeam