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Question About PROTEIN/CREATININE RATIO

A DiabetesTeam Member asked a question 💭
Turlock, CA

Hello to all my friends,

Sorry I have been so busy and haven’t been able to talk to you all.

I got my lab results and my PROTEIN/CREATININE RATIO is 0.194. It is marked “high”. I researched the whole internet about this and it mentions that if the result is less than 0.2mg/mg, it is normal. However, Quest Diagnostic range is between .025-.148. So I am kind of confused. I haven’t received any calls from my doctor either. Do you guys have any info on this? I would really appreciate if you can… read more

March 12, 2023
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A DiabetesTeam Member

My ACR was 35 on the last lab result(oct. of 2022) which is supposed to be less than 30. Just a little high. And Protein/creatinine for this lab which is 0.194. He didn't request the Albumin/creatinine ratio test for me this time. He prescribed me jardiance 10mg along with kerendia, 6 months ago and they are both for Kidney functionality. We all know that how bad Diabetes can effect kidneys. So looks like those prescriptions are helping me. We are all trying our best, I read that hard core exercise can increase protein levels at some point. Not sure if that is true. I play soccer twice a week and I think every session of soccer, is equal to 3 gym workouts the way we play. Very intense !!! anyways, it was great talking to you. I learned a lot from you,

Best Regards,
Tony

March 12, 2023
A DiabetesTeam Member

That's perfect - the Doc will dissect your ACR since it's a ratio between Albumin (some protein that tells you how well the liver and kidneys are working) and Creatinine (muscle waste)

If either of those high (or if albumin is low) that will mess with your ACR

But your eGFR says your kidneys are perfect

March 12, 2023 (edited)
A DiabetesTeam Member

It really depends on the "reference standard" that the Lab is using for it's reporting

The reference for all my ACR tests (forever) has always been under 0.2 with mine usually coming in at 0.05 or 0.06

The test is looking to see how well your kidneys are working and the Lab that did your test may have more stringent ranges in an attempt to catch a potential problem earlier (??)

In any event you are close to the typical standard at 0.194 but this doesn't always mean an issue. It really must be compared to your previous tests and future tests

Last year I was working on a very physically demanding project (not used to working that hard anymore) for a period of about 14 weeks. Strenuous physical activity causes you to burn up muscle and it is reflected in the ACR test as it was in my case (3 times normal ACR) but returned to "my normal" the next test

The ACR must be looked at in concert with an eGFR test - if both are abnormal and in agreement you have a kidney issue - if they disagree then generally all is fine

My eGFR (77) would equate to Stage 2 "mildly decreased kidney function" but my ACR being low normal says "nothing to worry about"

March 12, 2023
A DiabetesTeam Member

Btw my eGFR is 100 which is within the range. Oh well, I guess I am ok then. I have doctors appointment on Tuesday so I will see what doctor’s input is on that.

Thanks again

March 12, 2023
A DiabetesTeam Member

Thanks so much for your great information. I really appreciate that.

March 12, 2023

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