@A DiabetesTeam Member each (brand) of Insulin is upwards of 99.8% "identical" to human insulin we produce ourselves, so it is beyond rare to get a reaction from the insulin itself

But that "little bit" is the specific preservative that the mfg uses and it's that preservative which can result in injection site irritation

The (irritation) is likely not dangerous but could be "pesky" so I would discuss it with the prescribing Doctor as there is a couple of (identical) alternatives which may alleviate the issue

If you are using Humulin N there is two alternatives, Novolin N and NPH which use different preservatives and may not cause the reaction

If you are using Humulin R then Novolin R is the direct alternative

Mentioned Users

A Diabete...

I’m on tresiba

@alankier that is an "L" type

So you are taking the "long acting" (Basil) Humulin so there is about a dozen alternatives that your doctor could swap this out with if you decide that the injection site discomfort is something you would rather not deal with and are willing to try a different brand

In terms of the popular types of Basil Insulin, the Humulin is NOT ONE of Them which is why I made the assumption you were on N or R

Lantus, Basaglar, Levemir and Tresiba combined probably have about 95% of the basil insulin market

Looks like I'm on L