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Jardiance And Other New Diabetic Drugs

A DiabetesTeam Member asked a question 💭
Otsego, MI

It seems that people I know who take Jardiance and Victoza and Trulicity seem to be able to eat more carbs than people just taking metformin or drugs like glipizide. Do these drugs allow you to eat more carbs and still keep your blood glucose in check?

February 6, 2023 (edited)
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A DiabetesTeam Member

Yes they can because of the way they work

The Jardiance removes blood sugar and salt through the kidneys (kinda vacuums it out) so your could eat more carb comparatively and have them "sucked out" - so more in but more out = same/better blood sugar levels

Victoza and Trulicity cause the user to produce insulin (self produced) for "longer then they would have naturally" - so extra insulin means either lower blood sugar if you change nothing or able to handle more carbs and still maybe trend a little lower.

But one of the secondary benefits of those two is they also effect a hormone that tells us "you are getting full" so a little less likely to overeat and the user loses a bit of weight - but basically, because they help produce more insulin you could eat more carbs and there would insulin there to deal with them (within your limitations and resistance)

Metformin does "nothing" to help with carb that you consume. It strictly controls sugar release by the liver to help control fasting and between meal sugars - less released by the liver, less to deal with - but has zip to do with insulin or dealing with carbs you stuff your throat

Glipizide is a Sulfonylurea (SU's) - really old class of drugs (80+ years old) is super good at forcing the pancreas to release more insulin - so any of the SU's would allow the user to eat more carbs then they could without taking the drug - so yes, also a drug that lets you eat more carbs then you could have and still get a level of control "if you so choose"

Typically now though, the SU's are a late stage drug seen more as a 'last ditch effort before insulin' because they are a little cumbersome to take and don't have the additional benefits of the Jardiance or Ozempic or the rest of the "new kids on the block" AND the SU's tend to lead to some weight gain - and they are so efficient at getting you to produce insulin that they can cause "deadly lows" if you overdose accidently or skip a meal etc

February 6, 2023
A DiabetesTeam Member

Lucky you elmo

February 25
A DiabetesTeam Member

I've been taking Metformin for 26yrs and I've never been sick.or had any problems with it PW

February 23
A DiabetesTeam Member

No rather not take pills but know I have too. When I started I took metformin it made me sick

February 9, 2023
A DiabetesTeam Member

Don't u think it's better to not eat too many carbs and take fewer chemical based drugs?

February 9, 2023

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