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What Does Ferritin Have To Do With Diabetes If At All?

A DiabetesTeam Member asked a question πŸ’­
Drakensberg

My most recent blood test has a disturbing result that I am still battling to understand. My ferritin level is almost 4 times higher than the max normal result. At the same time my iron levels are at the bottom end of normal as are my iron saturation levels. I gather that this ferritin reading needs to be taken seriously. Seems strange that my body has high iron storage (ferritin) but lowish iron a nd low iron saturation. As a result I have now had an ultrasound scan of my abdomen that shows an… read more

June 4
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A DiabetesTeam Member

You lost almost 70 pounds in 6 months - that is a lot of weight in a short period of time (I lost 60 over about 10 months and that was considered "fast" by the Dietitian)

That kind of loss can increase ferritin levels all on it's own and the Doc tested your iron which proved that while it's on the low end of normal, it's not anemia that is causing the elevated levels

Fairly rapid weight loss of that scale (over 30 lbs) can also "initially" elevate your Cholesterol - and the "bad" can get way high but you would typically see a lowering of eGFR, Blood Pressure and Creatinine levels

I would wait for the "re-test" the Doc has ordered before you start sweating things "Because" the weight loss is a valid reason all by itself

Sometimes I do very physically intense work for a couple weeks/month and it jacks my creatinine levels AND my eGFR falls making it "look" like my CKD has progressed from Stage 2. But a retest a few weeks after I'm "not" slugging my guts out shows my numbers returned to (my) normal

It is a little un-nerving even when you have a "suspect", so just try to relax until your next blood work - worrying is bad for blood sugar levels and the answer is going to be the same 90 days from now whether you worry or not...

June 4 (edited)
A DiabetesTeam Member

@A DiabetesTeam Member.my brother in law has haemochromatosis ,so I have a little knowledge.
Raised ferritin levels are a sign of inflammation.( Like an underlying infection)
Conditions which may cause it
Alcohol use disorder
Non alcoholic fatty liver disease
Rheumatoid arthritis
Overactive thyroid
Various cancers
Treatment is chelated iron
Eat more dark green leafy veg and low inflammatory foods
Don't eat
Alcohol
Animal fat
Blood containing foods like black pudding
Citrus fruit/ juice except in moderation between meals
Fermented food like kimchi,pickles, sauerkraut
Ma
Greater than 300 Ng/mL is abnormal in men.but almost 50%people have levels 200-1000ng/mL
Doc needs to persevere,refer you.
Some research going on to use raised ferritin levels in diagnosis of diabetes.
Raised levels associated with diabetes complications like retinopathy, nephropathy and vascular dysfunction

June 4 (edited)
A DiabetesTeam Member

I'm not Hkc,or GrahLamb,but elevated serum ferritin levels are associated with insulin resistance. Increased ferritin levels in association with diabetic complications such as retinopathy, nephropathy, and vascular dysfunction in people with diabetes mellitus. Here are some examples that will cause high ferritin level's. Alcohol use, autoimmune diseases, and diabetes mellitus,certain blood cancers, obesity, overactive thyroid, adult onset Still's disease, cirrhosis of the liver. Normal 30-200 ng/ ml in women. 30-300 ng/ ml in men. There is a lot of information about ferritin levels. Hope this was helpful.

June 4

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